The fine structure of shape tuning in area V4.

The fine structure of shape tuning in area V4.
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DOI:
10.1016/j.neuron.2013.04.016
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发表时间:
2013-06-19
期刊:
影响因子:
16.2
通讯作者:
Mitchell JF
Mitchell JF
中科院分区:
医学1区
文献类型:
--
作者:
Nandy AS;Sharpee TO;Reynolds JH;Mitchell JF

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之前的研究表明,V4区的神经元参与中等复杂性形状的处理,并且对曲率敏感。这些研究还表明,曲率调谐神经元是位置不变的。我们试图研究赋予V4神经元这些特性的机制。与以前的研究一致,我们发现,在整个RF中,对最喜欢的刺激和最不喜欢的刺激的反应等级顺序被保留下来。然而,对形状调整的细粒度分析揭示了一个令人惊讶的结果:调整到高度弯曲形状的V4神经元表现出非常有限的平移不变性。在精细的空间尺度上,这些神经元在方向上表现出局部变化。相比之下,喜欢直线轮廓的神经元表现出空间不变的方向调整和均匀的精细尺度方向图。这两种模式都与一个简单的方向池模型相一致,分别从早期视觉区域继承的同质或异质方向图的池中调整直线或曲线形状。
Previous studies have shown that neurons in area V4 are involved in the processing of shapes of intermediate complexity and are sensitive to curvature. These studies also suggest that curvature tuned neurons are position-invariant. We sought to examine the mechanisms that endow V4 neurons with these properties. Consistent with previous studies, we found that response rank•order to the most• and least•preferred stimuli were preserved throughout the RF. However, a fine-grained analysis of shape tuning revealed a surprising result: V4 neurons tuned to highly curved shapes exhibit very limited translation invariance. At a fine spatial scale, these neurons exhibit local variation in orientation. In contrast, neurons that prefer straight contours exhibit spatially-invariant orientation tuning, and homogenous fine-scale orientation maps. Both these patterns are consistent with a simple orientation-pooling model, with tuning for straight or curved shapes resulting, respectively, from pooling of homogenous or heterogeneous orientation maps inherited from early visual areas.
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