Gold-catalyzed intramolecular carbocyclization of alkynyl ketones leading to highly substituted cyclic enones
Gold-catalyzed intramolecular carbocyclization of alkynyl ketones leading to highly substituted cyclic enones
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DOI：
10.1021/ol702455v
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发表时间：
2007-12-06
期刊：
影响因子：
5.2
通讯作者：
Yamamoto, Yoshinori
中科院分区：
文献类型：
--
作者：
Jin, Tienan;Yamamoto, Yoshinori
内炔基酮1（n = 1）在组合催化剂AuCl（3）和AgSbF6下的反应以良好至高产率得到烯酮2，而末端炔基酮1（n = 0）在组合催化剂AuCl 3和AgOTf下的反应得到环状烯酮3。
The reaction of the internal alkynyl ketones 1 (n = 1) under the combined catalyst, AUCl(3) and AgSbF6, gave the enones 2 in good to high yields, whereas that of the terminal alkynyl ketones 1 (n = 0) under the combined catalyst, AuCl3 and AgOTf, afforded the cyclic enones 3.