Secondary prevention of HIV infection: the current state of prevention for positives.
Secondary prevention of HIV infection: the current state of prevention for positives.
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DOI:
10.1097/coh.0b013e32832c7ce5
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发表时间:
2009-07
影响因子:
4.1
通讯作者:
Smith L
中科院分区:
文献类型:
--
作者:
Fisher JD;Smith L
To provide a state-of-the-science review of the literature on secondary prevention of HIV infection, or “prevention for positives” (PfP) interventions. Early work on prevention for positives focused on understanding the dynamics of risky behavior among People Living with HIV/AIDS (PLWH) and on designing, implementing, and evaluating a limited number of interventions to promote safer sexual and drug use behavior in this population (i.e., PfP interventions). Previous meta- analyses demonstrated that PfP interventions can effectively promote safer behavior. However, the understanding of risk dynamics among PLWH, and the extant number and breadth of effective PfP interventions, were scant. Recent work has addressed some of these problems, yielding greater understanding of risk dynamics and providing additional, effective, interventions. Still, only a modest number of recent, rigorously evaluated, effective interventions have been identified. New ideas for creating stronger, more integrated, and effective PfP interventions have emerged which will guide future intervention research and practice. There remains much to be done to understand why, when, and under what conditions PLWH practice risk. Substantial work also needs to be performed to design, implement, rigorously evaluate, and when effective, to disseminate widely, additional, evidence-based, PfP interventions targeting diverse populations. Directing such interventions to populations of PLWH at greatest risk for transmission of HIV has the potential to yield significant impact on the pandemic.