Magnetic Actuation Multifunctional Platform Combining Microdroplets Delivery and Stirring
Magnetic Actuation Multifunctional Platform Combining Microdroplets Delivery and Stirring
复制标题
结合微滴输送和搅拌的磁驱动多功能平台
DOI：
10.1021/acsami.9b18957
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发表时间：
2019
影响因子：
9.5
通讯作者：
Ye Tian
中科院分区：
文献类型：
--
作者：
He Liu;Shuang Zheng;Xuan Yang;Wenbo Liao;Can Wang;Weining Miao;Jiayue Tang;Dianyu Wang;Ye Tian
化学反应、生物分析等多种实验室操作迫切需要多功能液滴操纵装置。然而，目前大多数实现可控液滴传输系统的技术主要依靠被动扩散进行混合，限制了其实际应用。在这里，我们开发了一种磁控光滑表面凹坑（MCDSS），通过重力和不对称液滴变形之间的协同作用，可以实现任意方向甚至上坡液滴传输。进一步的实验表明，我们的系统还可以用于搅拌微滴，并将混合速度加快一百倍以上。此外，微搅拌策略有助于避免非均相反应中局部不均匀的沉淀或气体产生。这种液滴输送和搅拌的组合可能在各个领域具有广阔的应用前景，例如芯片实验室平台和微引擎。
Multifunctional droplets manipulation devices are in urgent need for various laboratory operations such as chemical reaction and biological analysis. However, most current techniques that achieved a controllable droplet transport system mainly rely on passive diffusion for mixing, limiting their practical applications. Here, we develop a magnetic controlled dimple on slippery surface (MCDSS) that enables arbitrary direction or even uphill droplet transport through the synergy between gravitational force and asymmetrical droplet deformation. Further experiments demonstrate that our system could also be used for stirring microdroplets and accelerating the mixing speed by more than one hundred times. In addition, the microstir strategy could help to avoid locally uneven production of precipitation or gas in heterogeneous reactions. This combination of droplet delivery and agitation may have a promising future for application in various fields, for example, laboratory-on-a-chip platforms and microengines.