Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update
Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update
复制标题
DOI：
10.1093/jac/dki079
复制
发表时间：
2005-05-01
影响因子：
5.2
通讯作者：
Drusano, GL
中科院分区：
文献类型：
--
作者：
Mouton, JW;Dudley, MN;Drusano, GL
近年来，人们对抗菌药物的药代动力学（PK）和药效学（PD）之间关系的兴趣有所增加。自从2年前我们发表了第一篇描述PK/PD术语的文章以来，该领域继续快速扩展，迫切需要更新。本文以统一的方式描述了抗菌药物及其单位的PK/PD表达的使用。
Interest in the relationships between the pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents has increased over recent years. Since the appearance 2 years ago of our first article describing terminology in PK/PD, the field has continued to expand rapidly, urgently requiring an update. This paper describes in a uniform manner the use of PK/PD expressions for antimicrobial agents, and their units.