Management of chronic graft-versus-host disease.

Management of chronic graft-versus-host disease.
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慢性移植物抗宿主病的治疗。

DOI:
--
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发表时间:
2011
影响因子:
1.1
通讯作者:
P. McKiernan
P. McKiernan
中科院分区:
医学4区
文献类型:
--
作者:
Melissa Baker;P. McKiernan

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慢性移植物抗宿主病(GVHD)是一种免疫介导的疾病,对造血干细胞移植后患者的生活质量和临床结局产生不利影响。GVHD的传统治疗包括长时间和大剂量的皮质类固醇;然而,这些药物与多种副作用有关。这篇文章描述了体外光分离治疗的能力,表现出节省类固醇的效果,可以减少由于类固醇治疗而导致的长期并发症。
Chronic graft-versus-host disease (GVHD) is an immune-mediated disorder that adversely affects quality of life and clinical outcomes in patients following hematopoietic stem cell transplantation. Conventional treatment of GVHD includes prolonged and high-dose corticosteroids; however, those drugs are associated with multiple side effects. This article describes the ability of extracorporeal photopheresis therapy to exhibit a steroid-sparing effect, which can reduce long-term complications as a consequence of steroid treatment.
DOI: 10.1182/blood-2005-03-1257
发表时间: 2005-10-15
期刊: BLOOD
影响因子: 20.3
作者:
Zorn, E;Kim, HT;Ritz, J
通讯作者: Ritz, J
DOI: 10.1056/nejmoa1004383
发表时间: 2010-11-25
期刊: The New England journal of medicine
影响因子: --
作者:
Gooley TA;Chien JW;Pergam SA;Hingorani S;Sorror ML;Boeckh M;Martin PJ;Sandmaier BM;Marr KA;Appelbaum FR;Storb R;McDonald GB
通讯作者: McDonald GB