Differences of the ipsilateral silent period in small hand muscles
Differences of the ipsilateral silent period in small hand muscles
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DOI：
10.1002/mus.20604
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发表时间：
2006-10-01
期刊：
影响因子：
3.4
通讯作者：
Ziemann, Ulf
中科院分区：
文献类型：
--
作者：
Jung, Patrick;Ziemann, Ulf
同侧静默期(Isp)被认为依赖于由胼胝体传递的活动，但同侧皮质脊髓通路也可能起作用。由于同侧皮质脊髓通路在小手部肌肉中的存在不同，我们比较了第一背侧骨间肌(FDi)和拇短展肌(APB)中的isp。20名健康受试者在同侧靶肌肉最大自主收缩时，经颅磁刺激一侧初级运动皮质，诱发ISP值。外国直接投资的ISP持续时间明显长于APB，因为在外国直接投资中出现了一个不规律的第二阶段抑制，而APB中没有这种抑制。虽然抑制的第一阶段是通过胼胝体传递的，但我们提供的证据表明，第二阶段是通过同侧皮质脊髓通路传递的。因此，对于特定的膝盖骨传导的评估，应以APB而不是FDI来测量ISP。
The ipsilateral silent period (iSP) is thought to depend on activity transmitted by the corpus callosum, but ipsilateral corticospinal pathways may also contribute. Because the presence of ipsilateral corticospinal pathways differs between small hand muscles, we compared the iSP in the first dorsal interosseous (FDI) and abductor pollicis brevis (APB) muscles. The iSP was elicited in 20 healthy subjects by focal transcranial magnetic stimulation of one primary motor cortex during maximal voluntary contraction of the ipsilateral target muscle. The iSP duration was significantly longer in the FDI than APB because of an irregularly occurring second phase of inhibition in the FDI that was absent in the APB. Although the first phase of inhibition is transmitted by the corpus callosum, we provide evidence that the second phase is mediated through ipsilateral corticospinal pathways. Therefore, for specific assessment of callosal conduction, the iSP should be measured in the APB rather than FDI.