Current Approach to Hepatocellular Carcinoma

Current Approach to Hepatocellular Carcinoma
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DOI:
10.1016/j.suc.2010.04.010
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发表时间:
2010-08-01
影响因子:
3.1
通讯作者:
Marsh, J. Wallis
Marsh, J. Wallis
中科院分区:
医学3区
文献类型:
--
作者:
Abrams, Peter;Marsh, J. Wallis

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肝细胞癌占所有原发性肝癌的80%,是全球第四大癌症相关死亡原因,部分肝切除术仍然是无肝硬变的部分肝细胞癌患者的最佳治疗选择,肝移植被公认为无肝外扩散和大血管侵犯的肝细胞癌和肝硬变患者的金标准。局部区域治疗适用于选择不适合手术的患者,其作为辅助治疗的作用仍有待前瞻性研究澄清。
Hepatocellular carcinoma (HCC) accounts for 80% of all primary liver cancers and ranks globally as the fourth leading cause of cancer-related death Partial hepatectomy remains the best treatment option for select patients with HCC without cirrhosis Liver transplantation is well established as the gold standard for patients with HCC and cirrhosis in the absence of extrahepatic spread and macrovascular invasion. Local regional therapy is indicated in select patients who are not surgical candidates, and its role as adjuvant therapy remains to be clarified by prospective studies