Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena.
Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena.
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用于实验室和工艺尺度混合现象动力学分析的计算机视觉。
DOI:
10.1021/acs.oprd.2c00216
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发表时间:
2022-11-18
影响因子:
3.4
通讯作者:
Reid, Marc
中科院分区:
文献类型:
--
作者:
Barrington, Henry;Dickinson, Alan;McGuire, Jake;Yan, Chunhui;Reid, Marc
A software platform for the computer vision-enabled analysis of mixing phenomena of relevance to process scale-up is described. By bringing new and known time-resolved mixing metrics under one platform, hitherto unavailable comparisons of pixel-derived mixing metrics are exemplified across non-chemical and chemical processes. The analytical methods described are applicable using any camera and across an appreciable range of reactor scales, from development through to process scale-up. A case study in nucleophilic aromatic substitution run on a 5 L scale in a stirred tank reactor shows how camera and offline concentration analyses can be correlated. In some cases, it can be shown that camera data hold the power to predict reaction progress.
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