Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena.

Computer Vision for Kinetic Analysis of Lab- and Process-Scale Mixing Phenomena.
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用于实验室和工艺尺度混合现象动力学分析的计算机视觉。

DOI:
10.1021/acs.oprd.2c00216
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发表时间:
2022-11-18
影响因子:
3.4
通讯作者:
Reid, Marc
Reid, Marc
中科院分区:
化学3区
文献类型:
--
作者:
Barrington, Henry;Dickinson, Alan;McGuire, Jake;Yan, Chunhui;Reid, Marc

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描述了一个用于计算机视觉分析与工艺放大相关的混合现象的软件平台。通过在一个平台下引入新的和已知的时间分辨混合指标,迄今为止无法在非化学和化学过程中对像素衍生的混合指标进行比较。所描述的分析方法适用于任何相机和反应器规模的相当大范围,从开发到工艺放大。在一个5升的搅拌槽反应器中进行亲核芳香族取代的案例研究显示了相机和离线浓度分析是如何相关的。在某些情况下,可以证明相机数据具有预测反应过程的能力。
A software platform for the computer vision-enabled analysis of mixing phenomena of relevance to process scale-up is described. By bringing new and known time-resolved mixing metrics under one platform, hitherto unavailable comparisons of pixel-derived mixing metrics are exemplified across non-chemical and chemical processes. The analytical methods described are applicable using any camera and across an appreciable range of reactor scales, from development through to process scale-up. A case study in nucleophilic aromatic substitution run on a 5 L scale in a stirred tank reactor shows how camera and offline concentration analyses can be correlated. In some cases, it can be shown that camera data hold the power to predict reaction progress.
DOI: 10.1039/b922446g
发表时间: 2010-01-01
期刊: ANALYST
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