Combining Two into One: A Dual-Function H5PV2Mo10O40@MOF-808 Composite as a Versatile Decontaminant for Sulfur Mustard and Soman.
Combining Two into One: A Dual-Function H5PV2Mo10O40@MOF-808 Composite as a Versatile Decontaminant for Sulfur Mustard and Soman.
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DOI：
10.1021/acs.inorgchem.0c01392
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发表时间：
2020-07
影响因子：
4.6
通讯作者：
Yuanyuan Zhou;Q. Gao;Lijuan Zhang;Yunshan Zhou;Yuxu Zhong;Jialin Yu;Jie Liu;Chengcheng Huang-Chengcheng-Hua
中科院分区：
文献类型：
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作者：
Yuanyuan Zhou;Q. Gao;Lijuan Zhang;Yunshan Zhou;Yuxu Zhong;Jialin Yu;Jie Liu;Chengcheng Huang-Chengcheng-Hua
由于战场环境的不可预测性，在同时降解芥子气和神经毒剂的情况下，最好只使用一种去污剂。本文通过简单的浸渍法制备了新型复合材料HPVMo@MOF-808 (HPVMo = H5PV2Mo10O40)，并对其进行了表征。结果表明，在环境条件下，HPVMo对HD （4 μL）和GD （4 μL）的最佳负荷下，复合材料（30 ~ 40 mg）的去污率分别为97.2% （120 min）和90.8% （30 min）。由于MOF-808与包裹均匀分散的HPVMo的组合/协同作用，该复合材料可以在单一体系中非常有效地将HD氧化为无毒产物，同时保留了MOF-808水解降解GD的固有优势。结果表明，该复合材料对HD和GD的去除率和半衰期分别为0.0231 min-1、30.13 min和0.0795 min-1、8.72 min。此外，以豚鼠和昆明小鼠为动物模型的实验结果表明，该复合材料对HD和GD具有有效的皮肤保护作用，在皮肤去污和保护方面具有很大的应用潜力。
Due to the unpredictable nature of a battlefield environment, in the simultaneous degradation of sulfur mustard and nerve agents it is preferable to use just one decontaminant. Herein, the new composite HPVMo@MOF-808 (HPVMo = H5PV2Mo10O40) was deliberately synthesized via a simple impregnation method and thoroughly characterized. The results showed that the decontamination rate of the composites (30-40 mg) with optimal HPVMo loadings for HD (4 μL) and GD (4 μL) under ambient conditions was 97.2% (within 120 min) and 90.8% (within 30 min), respectively. Due to the combinational/synergistic effect of MOF-808 and encapsulated homogeneously dispersed HPVMo, the composite can very efficiently oxidize HD to nontoxic products in a single system, while retaining the inherent excellence of MOF-808 in hydrolytically degrading GD. The decontamination process was found to follow first-order reaction kinetics, and the rate constant and half-life of the composite for HD and GD were 0.0231 min-1, 30.13 min and 0.0795 min-1, 8.72 min, respectively. In addition, experimental results in guinea pigs and Kunming mice used as animal models showed that the composite provided effective skin protection against HD and GD, showing great potential for application in skin decontamination and protection.