Influence of pH and oxygen-inhibited layer on fluoride release properties of fluoride sealant.
Influence of pH and oxygen-inhibited layer on fluoride release properties of fluoride sealant.
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pH值和阻氧层对氟化密封胶释氟性能的影响。
DOI：
10.1016/j.jdent.2006.09.005
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发表时间：
2007
影响因子：
4.4
通讯作者：
Anusavice,KJ
中科院分区：
文献类型：
--
作者：
Shen,C;Shokry,TE;Anusavice,KJ
目的本研究测试了光固化甲基丙烯酸酯树脂上的氧抑制层和存储介质的 pH 值会显着增加氟化物牙科密封剂的初始氟化物释放和长期释放率的假设。方法 48 个圆盘（直径 16 毫米×厚 1 毫米）由 FluroShield（<5wt% NaF）和 Helioseal F（<30wt% 氟硅酸盐玻璃）密封剂制成。对于每种密封剂，24 个圆盘通过覆盖表面的 Mylar® 条进行固化，其余 24 个圆盘在空气中固化，从而形成氧抑制表面。 24 盘组中的每个样本单独储存在 25 mL 的小瓶中，并分为四个 6 瓶组，分别接收 10 mL pH4–pH7（指定 pH 4–7）乳酸缓冲溶液。缓冲溶液定期更换，最多 121 天。随着时间的推移累积氟化物释放量用于确定短期和长期释放的系数。结果双向方差分析表明，除了 NaF 密封剂的短期释放外，两种密封剂的平均系数值均受到固化条件 (p<0.0001) 和 pH (p<0.0001) 的显着影响。氟硅酸盐玻璃密封胶的短期释放持续时间要长得多。 结论 pH 值和密封胶中氟化物的来源对氟化物释放起着重要作用。
OBJECTIVESThis study tested the hypothesis that the oxygen-inhibited layer on a light-cured methacrylate based resin and the pH of the storage medium would increase significantly the initial fluoride release and long-term release rate from fluoride dental sealant.METHODSForty-eight discs (16-mm diameter×1-mm thick) were made from FluroShield (<5wt% NaF) and Helioseal F (<30wt% fluorosilicate glass) sealants. For each sealant, 24 discs were cured through a Mylar®strip that covered the surface and the remaining 24 discs were cured in air allowing formation of the oxygen-inhibited surface. Each specimen in the 24-disc groups was stored individually in 25-mL vials, and divided into four six-vial groups to receive 10mL of pH4–pH7 (designation of pH 4–7) lactate buffer solutions. The buffer solutions were replaced periodically up to 121 days. The cumulative fluoride release over time was used to determine the coefficients for short-term and long-term release.RESULTSTwo-way ANOVA showed that the mean coefficient values for either sealant were significantly influenced by the curing condition (p<0.0001) and pH (p<0.0001), except for short-term release from NaF sealant. The duration of short-term release was much longer for the fluorosilicate glass sealant.CONCLUSIONSBoth pH and the source of fluoride source incorporated in the sealant play significant roles in fluoride release.
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影响因子：
5
作者：
Geurtsen, W;Leyhausen, G;Garcia-Godoy, F
通讯作者：
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DOI：
--
发表时间：
2004
期刊：
Bull Tokyo dent Coll 45
影响因子：
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影响因子：
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作者：
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F. Koray