Ultrasound characteristics of cervical lesions in patients with radioiodine refractory differentiated thyroid cancer

Ultrasound characteristics of cervical lesions in patients with radioiodine refractory differentiated thyroid cancer
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DOI:
10.1097/md.0000000000017876
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发表时间:
2019-11-01
期刊:
影响因子:
1.6
通讯作者:
Zhang, Bo
Zhang, Bo
中科院分区:
医学4区
文献类型:
--
作者:
Gao, Luying;Lin, Yansong;Zhang, Bo

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放射性碘难治性(RAIR)是甲状腺癌相关死亡的主要原因。为避免不必要的放射性碘(Radioiodine,RAI)治疗,及时发现RAIR病例,为患者争取有效治疗时间,评价RAIR分化型甲状腺癌(differentiated thyroid cancer,DTC)颈部转移淋巴结的超声特征。对59例非RAIR-DTC患者的颈部淋巴结转移和RAIR-DTC患者的颈部病变进行了超声检查,发现17例患者中15例(88.3%)有颈部淋巴结转移。RAIR-DTC组宫颈病变平均2.0cm,大于非RAIR-DTC组1.30cm。RAIR组多发病灶多见,可见血流者多见,强回声灶少见(P
Radioiodine refractory (RAIR) is the major cause of thyroid cancer-related death. In order to avoid needless Radioiodine (RAI) therapy, recognizing the RAIR cases in time is important for the patients to obtain more time for the effective therapy.Evaluate the ultrasound features of cervical metastatic lymph node in patients with RAIR differentiated thyroid cancer (DTC).Seventeen adult patients with histologically confirmed locally advanced or metastatic RAIR-DTC were prospectively enrolled. The ultrasound (US) characteristics of cervical lesions in patients with the RAIR-DTC were compared with cervical lymph node metastasis from 59 non RAIR-DTC cases.Among the 17 patients, cervical lymph node metastasis was found in 15 patients (88.3%). The cervical lesions of RAIR-DTC (mean size, 2.0cm) were larger than that in non RAIR-DTC group (mean size, 1.30 cm). More multiple lesions and more lesions with visible flow were found in the RAIR Group, while fewer hyperechogenic punctuations were found in RAIR group (P