Refeeding hypophosphatemia in hospitalized adolescents with anorexia nervosa: a position statement of the Society for Adolescent Health and Medicine.
Refeeding hypophosphatemia in hospitalized adolescents with anorexia nervosa: a position statement of the Society for Adolescent Health and Medicine.
复制标题
DOI：
10.1016/j.jadohealth.2014.06.010
复制
发表时间：
2014-09
期刊：
影响因子：
--
通讯作者：
Society for Adolescent Health and Medicine
中科院分区：
文献类型：
--
作者：
Society for Adolescent Health and Medicine
再喂养综合征描述了营养不良患者在再喂养过程中可能发生的临床和代谢紊乱。 60 多年前首次描述，再喂养综合征发生在与营养不良 (1-4) 相关的疾病中，包括神经性厌食症 (AN)。(5-13) 再喂养综合征很复杂，由多种代谢和临床特征组成。临床特征包括心律失常、心力衰竭或心脏骤停、肌肉无力、溶血性贫血、谵妄、癫痫发作、昏迷和猝死，这些症状可能在营养康复开始后数天至数周内发生（14）。再喂养综合征的标志性生化特征是低磷血症，也称为再喂养低磷血症(RH)。再喂养低磷血症被认为在再喂养综合征中发挥重要作用(14)。饥饿期间，糖原储存耗尽后，脂肪、蛋白质和肌肉的分解代谢提供了主要的能量来源。一旦开始重新进食，碳水化合物就成为能量产生的主要底物。随着碳水化合物的重新引入，胰岛素分泌导致电解质流入细胞。需要磷
Refeeding syndrome describes the clinical and metabolic derangements that can occur during the refeeding of a malnourished patient. First described over 60 years ago, refeeding syndrome occurs in conditions associated with malnutrition (1–4), including anorexia nervosa (AN).(5–13) Refeeding syndrome is complex and consists of a variety of metabolic and clinical features. The clinical features include cardiac arrhythmias, cardiac failure or arrest, muscle weakness, hemolytic anemia, delirium, seizures, coma and sudden death that can occur days to weeks after the initiation of nutritional rehabilitation (14). The hallmark biochemical feature of refeeding syndrome is hypophosphatemia, also referred to as refeeding hypophosphatemia (RH).Refeeding hypophosphatemia is thought to play an important role in the refeeding syndrome (14). During starvation, after glycogen stores have been depleted, catabolism of fat, protein and muscle provides the major source of energy. Once refeeding is initiated, carbohydrates become the major substrate for energy production. With reintroduction of carbohydrates, insulin secretion causes an influx of electrolytes into the cells. Phosphorus is required for
登录
查看更多内容
影响因子：
7.6
作者：
Garber, Andrea K.;Michihata, Nobuaki;Moscicki, Anna-Barbara
通讯作者：
Moscicki, Anna-Barbara
影响因子：
6.3
作者：
Gentile, Maria Gabriella;Pastorelli, Paola;Collimedaglia, Simona
通讯作者：
Collimedaglia, Simona
影响因子：
7.6
作者：
Kohn, MR;Golden, NH;Shenker, IR
通讯作者：
Shenker, IR
影响因子：
7.6
作者：
Golden, Neville H.;Keane-Miller, Casey;Kapphahn, Cynthia J.
通讯作者：
Kapphahn, Cynthia J.
影响因子：
11.4
作者：
BEUMONT, PJV;LARGE, M
通讯作者：
LARGE, M