Epidemiology of Herpes Zoster Infection among Patients Treated in Primary Care Centres in the Valencian Community (Spain)
Epidemiology of Herpes Zoster Infection among Patients Treated in Primary Care Centres in the Valencian Community (Spain)
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DOI：
10.1186/1471-2296-11-33
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发表时间：
2010-05-06
影响因子：
2.9
通讯作者：
Navarro-Perez, Jorge
中科院分区：
文献类型：
--
作者：
Cebrian-Cuenca, Ana M.;Diez-Domingo, Javier;Navarro-Perez, Jorge
背景：西班牙带状疱疹（HZ）的流行病学资料很少。本研究的主要目标是估计HZ在瓦伦西亚自治区的年发病率。方法：从2006年12月1日（st）至2007年12月1日，在24个初级卫生保健中心进行了前瞻性研究，这些中心共为36，030名年龄> 14岁的人提供护理。我们纳入了在一年研究期间在这些中心就诊的临床诊断为HZ的所有成人患者。人口统计学（即，结果：共发现146例HZ，其中146例为非典型增生，146例为非典型增生，146例为典型增生。HZ的年发病率为4.1/1，000名> 14岁的个体（95%置信区间[CI]：3.4-4.7）。HZ病例主要是单侧的，最常受影响的是妇女和生活在农村地区的人。最常报告的症状是疼痛、感觉迟钝和瘙痒。共有46%的患者还患有基础疾病（例如，慢性疾病和/或恶性肿瘤），24%的患者出现并发症，主要是眼部并发症。共有91%的患者接受了抗病毒药物治疗。从症状发作到诊断的中位时间为6.3天（范围：2.0-8.3）。结论：HZ是一种常见的疾病，在我们的地区（特别是在老年人口），造成显着的临床负担的初级保健提供者。
Background: There is little available data regarding the epidemiology of herpes zoster (HZ) in Spain. This study's main goal was to estimate the annual incidence of HZ in the Autonomous Community of Valencia.Methods: From December 1(st) 2006 to December 1(st) 2007, a prospective study was carried out in 24 primary health care centres that together provide care for a population of 36,030 persons aged > 14 years. We included all adult patients with a clinical diagnosis of HZ who were seen at these centres during the one-year study period. Demographic (i.e., age, gender, and area of residence) and clinical data were also collected from these patients.Results: A total of 146 cases of HZ were identified during the study period. The annual incidence of HZ was 4.1/1,000 individuals > 14 years of age (95% confidence interval [CI]: 3.4-4.7). Cases of HZ were predominantly unilateral and most commonly affected women and people living in rural areas. The most frequently reported symptoms were pain, dysesthesia and itching. A total of 46% of patients also had underlying illnesses (e.g., chronic diseases and/or malignancy) and 24% of patients experienced complications, which were mostly ocular in nature. A total of 91% of patients were treated with antiviral drugs. The median time from symptoms onset to diagnosis was 6.3 days (range: 2.0-8.3).Conclusions: HZ is a common illness in our region (especially in the older population) that causes a significant clinical burden on primary care providers.