ACTIVE AND PASSIVE MECHANICAL CHARACTERISTICS OF BOVINE MESENTERIC LYMPHATICS
ACTIVE AND PASSIVE MECHANICAL CHARACTERISTICS OF BOVINE MESENTERIC LYMPHATICS
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DOI：
10.1152/ajpheart.1980.239.1.h88
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发表时间：
1980-01-01
影响因子：
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通讯作者：
SAKAGUCHI, M
中科院分区：
文献类型：
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作者：
OHHASHI, T;AZUMA, T;SAKAGUCHI, M
牛肠系膜淋巴管的压力-容积和压力-半径关系与静脉相似。弹性体的周向弹性模量为4.2 × 10 - 4。104至2.7 ×105达因/平方厘米。淋巴管壁扩张引起自发性收缩。收缩力在扩张早期增加，在达到最佳腔内压力后下降。自发活动受细胞壁变形速率的影响。自发活动的起搏点似乎位于淋巴管入口阀附近的壁中。放射性以4 - 5 mm/s的速度传播。淋巴管的射血分数在45 - 65%之间。淋巴瓣的耐受极限为68.1 ± 0.01。7.6 cm H2O，在约外径为3 mm。淋巴管平滑肌似乎在管壁的弹性行为和自发活动的调节中起主要作用，从而显著影响被动和主动淋巴转运。
Pressure-volume and pressure-radius relationships in lymphangions isolated from bovine mesenteric lymphatics were similar in pattern with those in the vein. Circumferential modulus of elasticity of the lymphatics ranged from 4.2 .times. 104 to 2.7 .times. 105 dyn/cm2. Spontaneous contractions were evoked by distension of lymphatic walls. The contractile force increased in early stages of distension and decreased after an optimal intraluminal pressure was attained. The spontaneous activity was affected by the rate of wall deformation. The pacemaker site of spontaneous activity seemed to be in the wall in the immediate vicinity of the inlet valve of a lymphangion. The activity propagated with a velocity of 4-5 mm/s. Ejection fraction of a lymphangion was between 45-65%. The endurance limit of the lymphatic valve was 68.1 .+-. 7.6 cmH2O in specimens of .apprx. 3 mm in outer diameter. Lymphatic smooth muscle seemed to play a major role in elastic behavior of the wall and in regulation of the spontaneous activity, thereby affecting significantly passive and active lymph transport.