CYTOCHALASIN-B - DOES IT AFFECT ACTIN-LIKE FILAMENTS
CYTOCHALASIN-B - DOES IT AFFECT ACTIN-LIKE FILAMENTS
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DOI：
10.1126/science.175.4023.774
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发表时间：
1972-01-01
期刊：
影响因子：
56.9
通讯作者：
BEHNKE, O
中科院分区：
文献类型：
--
作者：
FORER, A;EMMERSEN, J;BEHNKE, O
使用体外系统测试细胞松弛素B的预期作用。在100倍于用于体内实验的浓度下，细胞松弛素B不引起F-肌动蛋白的分解，不抑制G-肌动蛋白向F-肌动蛋白的转化，不抑制重酶解肌球蛋白与F-肌动蛋白的结合，并且不抑制三磷酸腺苷诱导的重酶解肌球蛋白从F-肌动蛋白的释放。
An in vitro system was used to test the purported action of cytochalasin B. At concentrations 100 times those used for experiments in vivo, cytochalasin B did not cause the breakdown of F-actin, did not inhibit the transformation of G-actin to F-actin, did not inhibit the binding of heavy meromyosin to F-actin, and did not inhibit the adenosine triphosphate-induced release of heavy meromyosin from F-actin.