Pulmonary vasculitis.
Pulmonary vasculitis.
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DOI：
10.1513/pats.200511-120jh
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发表时间：
2006-01-01
期刊：
影响因子：
--
通讯作者：
Brown, Kevin K
中科院分区：
文献类型：
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作者：
Brown, Kevin K
肺血管炎是一种以血管破坏为病理特征的疾病。每种疾病的临床表现都是由受影响血管的大小、类型和位置来定义的。这些疾病的临床方法取决于一个精明的临床医生考虑诊断和确定临床、放射学、实验室和病理异常的特定模式。肺部受累最常见于原发性、特发性、小血管或抗中性粒细胞细胞质抗体相关的血管增生；韦格纳肉芽肿病，显微镜下多血管炎和丘格-施特劳斯综合征。然而，原发性、特发性中、大血管炎、原发性免疫复合物介导的血管炎和继发性血管炎均可表现为肺部受累。在这篇文章中，我们集中在更常见的，抗中性粒细胞细胞质抗体相关疾病，血管增生。
Pulmonary vasculitis describes a number of distinct disorders that are pathologically characterized by the destruction of blood vessels. The clinical manifestations of each disorder are defined by the size, type, and location of the affected vasculature. The clinical approach to these disorders rests upon an astute clinician considering the diagnosis and identifying the specific patterns of clinical, radiologic, laboratory, and pathologic abnormalities. Lung involvement is most commonly seen with the primary, idiopathic, small-vessel, or antineutrophil cytoplasmic antibody-associated vasculitides; Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome. However, primary, idiopathic medium and large-vessel vasculitis, primary immune complex-mediated vasculitis, and secondary vasculitis are all capable of presenting with lung involvement. In this article, we focus on the more common, antineutrophil cytoplasmic antibody-associated disorder, vasculitides.