HEPATITIS-C VIRUS-ANTIBODIES IN SOUTHERN AFRICAN BLACKS WITH HEPATOCELLULAR-CARCINOMA
HEPATITIS-C VIRUS-ANTIBODIES IN SOUTHERN AFRICAN BLACKS WITH HEPATOCELLULAR-CARCINOMA
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DOI：
10.1016/0140-6736(90)90474-j
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发表时间：
1990-04-14
期刊：
影响因子：
168.9
通讯作者：
KUO, G
中科院分区：
文献类型：
--
作者：
KEW, MC;HOUGHTON, M;KUO, G
研究了380名患有肝细胞癌的南部非洲黑人和152名对照。在110例患者和1例对照者中发现了丙型肝炎病毒（HCV）抗体。184例患者有目前感染B型肝炎病毒（HBV）的证据，122例患者过去曾感染过该病毒。只有47例患者没有HCV或HBV感染的标志物。在HCV阳性患者中，女性和城市居民所占比例较高，平均年龄较高。在南部非洲，HCV与肝细胞癌相关，但HBV在较高比例的患者中存在。
380 southern African blacks with hepatocellular carcinoma and 152 controls were studied. Antibodies to hepatitis C virus (HCV) were found in 110 patients and 1 control. 184 patients had evidence of current infection with hepatitis B virus (HBV) and 122 had had infection with this virus in the past. Only 47 patients had no markers of HCV or HBV infection. Among patietns positive for HCV, there was a higher proportion of women and urban dwellers, and the average age was higher. In southern Africa, HCV is associated with hepatocellular carcinoma but HBV is present in a higher proportion of patients.