The bacteriologic yield in children with intrathoracic tuberculosis

The bacteriologic yield in children with intrathoracic tuberculosis
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DOI:
10.1086/502652
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发表时间:
2006-04-15
影响因子:
11.8
通讯作者:
Beyers, N
Beyers, N
中科院分区:
医学1区
文献类型:
--
作者:
Marais, BJ;Hesseling, AC;Beyers, N

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本报告记录了在结核病高度流行地区接受胸内结核治疗的儿童的细菌学产率。共有307名儿童被纳入研究,196名儿童中有122名(62.2%)获得细菌学确认。69名患有无并发症淋巴结疾病的儿童的细菌学检出率最低(24名[34.8%]得到细菌学确认)。高的总体细菌学产量表明,需要重新评估的价值,细菌学为基础的方法来诊断儿童胸内结核,特别是在地方性地区,他们经常出现与先进的疾病。
This report documents the bacteriologic yield in children who received treatment for intrathoracic tuberculosis in an area where it is highly endemic. A total of 307 children were included in the study, and bacteriologic confirmation was achieved in 122 (62.2%) of 196 children from whom specimens were collected. The lowest bacteriologic yield was recorded for the 69 children with uncomplicated lymph node disease ( 24 [34.8%] had bacteriologic confirmation). The high overall bacteriologic yield indicates the need to reassess the value of bacteriology-based approaches to diagnosis of intrathoracic tuberculosis in children, particularly in areas of endemicity where they frequently present with advanced disease.