TRYPANOSOMA SPP, LEISHMANIA SPP AND LEPTOMONAS SPP - ENZYMES OF ORNITHINE-ARGININE METABOLISM
TRYPANOSOMA SPP, LEISHMANIA SPP AND LEPTOMONAS SPP - ENZYMES OF ORNITHINE-ARGININE METABOLISM
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DOI：
10.1016/0014-4894(78)90125-x
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发表时间：
1978-01-01
影响因子：
2.1
通讯作者：
FIGUEIREDO, EN
中科院分区：
文献类型：
--
作者：
CAMARGO, EP;COELHO, JA;FIGUEIREDO, EN
对克氏锥虫、梅加锥虫、康氏锥虫、杜氏利什曼原虫、巴西利什曼原虫、塞莫氏细小单胞菌、胶状锥虫和萨缪利锥虫8种鞭毛锥虫的精氨酸-鸟氨酸代谢酶进行了检测。精氨酸酶存在于利什曼原虫属和细粒单胞菌属中。瓜氨酸水解酶仅见于细粒单胞菌。锥虫属没有呈现任何这些酶。鸟氨酸氨基甲酰基转移酶和精氨酸琥珀酸裂解酶仅见于具有精氨酸脱亚胺酶的沙美利。除了L·Samueli外，其他种似乎呈现出统一的酶结构，这是它们的属所特有的，不同于已知的其他锥虫属的酶类型。讨论了这些发现在分类学方面的潜在用途。
Eight species of trypanosomatid flagellates, Trypanosoma cruzi, T. mega, T. conorhini, Leishmania donovani, L. braziliensis, Leptomonas seymouri, L. collosoma and L. samueli, were examined for the presence of enzymes of the arginine-ornithine metabolism. Arginase was found in species of the genera Leishmania and Leptomonas. Citrulline hydrolase was found only in species of Leptomonas. Trypanosoma spp. did not present any of these enzymes. Ornithine carbamoyltransferase and argininosuccinate lyase were found only in L. samueli, which also possessed arginine deiminase. With the sole exception of L. samueli the other species seemed to present a uniform enzyme constitution, peculiar to their genera and different from the enzyme patterns of other genera of trypanosomatids already known. The potential usefulness of these findings for taxonomical purposes was discussed.