The effect of 2,2’,4,4’-Tetrabromodiphenyl ether (BDE-47) on locomotor behaviour and muscle physiology of the sea cucumber Apostichopus japonicus
The effect of 2,2’,4,4’-Tetrabromodiphenyl ether (BDE-47) on locomotor behaviour and muscle physiology of the sea cucumber Apostichopus japonicus
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2,2-,4,4-四溴二苯醚 (BDE-47) 对仿刺参运动行为和肌肉生理的影响
DOI：
10.1016/j.marpolbul.2022.114198
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发表时间：
2011
影响因子：
5.8
通讯作者：
Hongsheng Yang
中科院分区：
文献类型：
--
作者：
Pengji Zhuo;Kui Ding;Beini Deng;Kaiqi Lai;Shuangli Zhang;Libin Zhang;Hongsheng Yang
2，2 ′，4，4 ′-四溴二苯醚（BDE-47）是多溴联苯醚的主要同系物，也是环境和动物样品中检出率较高的持久性有机污染物。迄今为止，关于BDE-47对海参运动的影响的研究很少。本研究采用超高效液相色谱-四极杆飞行时间质谱法，研究了不同浓度的BDE-47（低浓度：0.1 μ g/L;中浓度：1.0 μ g/L;高浓度：10.0 μg/L）对仿刺参（Apostichopus japonicus）运动的影响，并评价了其肌肉生理变化。行为研究表明，中等浓度和高浓度BDE-47组在接触一天后，平均和最大移动速度均大幅下降。此外，55代谢物的水平进行了鉴定，并在纵肌的A。japonicus暴露于BDE-47。牛磺酸和去甲肾上腺素水平的变化表明，BDE-47对A. - 是的
The 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) is the predominant congener of polybrominated diphenyl ethers, and it is also a persistent organic pollutant that with a higher detection rate in samples from environment and animals. To date, there have been few studies of the effects of BDE-47 on locomotion in sea cucumbers. In this study, we investigated the influence of different concentrations of BDE-47 (low: 0.1 μg/L; moderate: 1.0 μg/L; high: 10.0 μg/L) on locomotion ofApostichopus japonicusand evaluated changes in their muscle physiology using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry. The behavioural studies showed that the average and maximum velocity of movement decreased significantly in both the moderate and high BDE-47 groups after 1 day of exposure. In addition, levels of 55 metabolites were identified and characterized in the longitudinal muscle ofA. japonicusexposed to BDE-47. The alteration of taurine and norepinephrine levels indicated that BDE-47 had drastic physiological effects on the longitudinal muscle ofA. japonicus.