Passive permeation of organic compounds through biological tissue: a non-steady-state theory.
Passive permeation of organic compounds through biological tissue: a non-steady-state theory.
复制标题
有机化合物通过生物组织的被动渗透:非稳态理论。
作者:
J. Penniston;L. Beckett;D. Bentley;C. Hansch
A theoretical analysis of the penetration of drug molecules to their sites of action in terms of their lipophilic character is presented. This analysis justifies the parabolic equations which have been used empirically to describe the relationship between effectiveness of drug and its lipophilic character.