Drug eluting coronary stent: in vitro evaluation of magnet resonance safety at 3 Tesla

Drug eluting coronary stent: in vitro evaluation of magnet resonance safety at 3 Tesla
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DOI:
10.1081/jcmr-200053588
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发表时间:
2005-04-01
影响因子:
6.4
通讯作者:
Forder, JR
Forder, JR
中科院分区:
医学2区
文献类型:
--
作者:
Shellock, FG;Forder, JR

文献摘要

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目的。评价药物洗脱冠状动脉支架在3特斯拉时的MR安全性。方法。评估药物洗脱冠状动脉支架(Endeavor,钴合金,Medtronic Vascular, Santa Rosa, CA)在3特斯拉下的磁场相互作用、加热和假像。使用发射/接收射频体线圈,整个体平均SAR为2.0 W/kg,在凝胶盐水填充体中使用支架评估mri相关加热。利用t1加权、自旋回波和梯度回波脉冲序列对伪影进行表征。结果。支架表现出轻微的磁场相互作用,不会引起迁移。加热不明显(+ 0.5℃)。如果感兴趣的区域位于同一区域或靠近支架,则伪影可能会产生问题(例如,对于t1加权的自旋回波脉冲序列,在大约16mm内;对于梯度回波脉冲序列,在大约23mm内)。结论。研究结果表明,使用这种钴合金为基础的药物洗脱冠状动脉支架的患者在3特斯拉或更低的频率下进行MRI检查是安全的。重要的是,由于相对缺乏磁场相互作用,MRI可以在植入后立即进行。
Purpose. To evaluate MR safety at 3 Tesla for a drug eluting coronary stent. Methods. A drug eluting coronary stent ( Endeavor, cobalt alloy, Medtronic Vascular, Santa Rosa, CA) was evaluated for magnetic field interactions, heating, and artifacts at 3 Tesla. MRI-related heating was assessed with the stent in a gelled saline-filled phantom using a transmit/received RF body coil with a whole body averaged SAR of 2.0 W/kg. Artifacts were characterized using T1-weighted, spin echo, and gradient echo pulse sequences. Results. The stent exhibited minor magnetic field interactions that will not cause migration. Heating was not substantial (+ 0.5 degrees C). Artifacts may create a problem if the area of interest is in the same area or close to the stent ( e. g., for a T1-weighted, spin echo pulse sequence, within approximately 16 mm; for a gradient echo pulse sequence, within approximately 23 mm). Conclusion. The findings indicated that it would be safe for a patient with this cobalt alloy-based, drug-eluting coronary stent to undergo MRI at 3 Tesla or less. Importantly, because of the relative lack of magnetic field interactions, MRI may be performed immediately after implantation.