Intraarterial chemotherapy of head and neck tumors.
Intraarterial chemotherapy of head and neck tumors.
复制标题
头颈部肿瘤的动脉内化疗。
DOI：
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
Helmuth Goepfere
中科院分区：
文献类型：
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作者：
Y. Lee;S. Wallace;Isaiah Dimerl;Helmuth Goepfere
41例晚期复发性或未经治疗的颈部肿瘤患者接受了颈外动脉内短期（1-1 1/2小时）顺铂灌注治疗，立即肿瘤缓解率为29.3%。单个颈外动脉范围内或范围外的肿瘤范围是影响肿瘤缓解率的唯一重要因素（57.1%与14.8%）。在放疗或手术前使用超选择性导管插入进行动脉化疗对某些患者是有益的。
Forty-one patients with advanced recurrent or untreated and neck tumors were treated with intraarterial short-term (1-1 1/2 hr) infusion of cisplatin into the external carotid artery, achieving an immediate tumor response rate of 29.3%. Tumor extent within or beyond the territory of a single external carotid artery was the only significant factor identified affecting the tumor response rate (57.1% vs. 14.8%). Treatment with intraarterial chemotherapy using superselective catheterization before irradiation or surgery is beneficial in some patients.