Maternal cigarette smoking during pregnancy is an independent predictor for symptoms of middle ear disease at five years' postdelivery
Maternal cigarette smoking during pregnancy is an independent predictor for symptoms of middle ear disease at five years' postdelivery
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DOI：
10.1542/peds.104.2.e16
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发表时间：
1999-08-01
期刊：
影响因子：
8
通讯作者：
Bor, W
中科院分区：
文献类型：
--
作者：
Stathis, SL;O'Callaghan, M;Bor, W
虽然越来越多的文献已经证明子宫内暴露于香烟烟雾和儿童发病率之间的联系，这种暴露与中耳疾病（MED）的程度是不确定的。我们假设子宫内暴露于香烟烟雾与MED风险增加相关，并旨在计算分娩后5年因妊娠期间吸烟而导致的疾病比例。在第一次产前检查时，8556名妇女参加了一项怀孕的前瞻性研究。母亲们在怀孕期间、出生时、产后6个月和5年接受了随访，并完成了一份详细的问卷，旨在评估急性（
Although an increasing body of literature has demonstrated a link between in utero exposure to cigarette smoke and childhood morbidity, the extent to which such exposure is associated with middle ear disease (MED) is less certain. We hypothesized that in utero exposure to cigarette smoke was associated with an increased risk of MED and aimed to calculate the proportion of disease at 5 years' postdelivery attributable to cigarette exposure during pregnancy.Methods. At their first antenatal session, 8556 women were enrolled in a prospective study of pregnancy. Mothers were followed during pregnancy, at birth, at 6 months' and at 5 years' postdelivery and completed a detailed questionnaire aimed at assessing the frequency of acute (