WEIGHT-LOSS EXPERIENCE OF BLACK-AND-WHITE PARTICIPANTS IN NHLBI-SPONSORED CLINICAL-TRIALS
WEIGHT-LOSS EXPERIENCE OF BLACK-AND-WHITE PARTICIPANTS IN NHLBI-SPONSORED CLINICAL-TRIALS
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DOI：
10.1093/ajcn/53.6.1631s
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发表时间：
1991-06-01
影响因子：
7.1
通讯作者：
WHELTON, PK
中科院分区：
文献类型：
--
作者：
KUMANYAKA, SK;OBARZANEK, E;WHELTON, PK
我们检查了两项随机多中心试验的种族特异性减肥结果：高血压预防试验（HPT）和高血压预防试验（TOHP）。在TOHP的18个月随访期间，黑人女性较基线的平均体重变化平均比白色女性低2.2 kg，在HPT的36个月随访期间，黑人女性较基线的平均体重变化平均低2.7 kg。TOHP组黑人的平均体重减轻比白色男性平均少2.0 kg，HPT组平均少1.4 kg。由于黑人对照受试者的体重增加更大，净体重减轻的比较（干预变化减去对照受试者的变化，种族内）显示出比积极治疗组中体重减轻的黑人-白人差异更小的显着差异。因此，相对于在没有干预的情况下增加的体重，黑人和白人的经历更相似。减肥的种族差异可能是由行为，社会文化，生物和程序因素的组合造成的。
We examined race-specific weight-loss results from two randomized, multicenter trials: the Hypertension Prevention Trial (HPT) and the Trials of Hypertension Prevention (TOHP). Mean weight change from baseline averaged 2.2 kg less in black women than in white women during 18 mo of follow-up in TOHP and 2.7 kg less during 36 mo of follow-up in HPT. Mean weight loss averaged 2.0 kg less in black than in white men in TOHP and 1.4 kg less in HPT. Because of greater weight gain in black control subjects, a comparison of net weight loss (change in intervention minus change in control participants, within-race) showed a less marked difference than did black-white differences in weight loss within the actively treated group. Thus, relative to weight that would have been gained without the intervention, the experience of blacks and whites was more similar. Racial differences in weight loss may result from a combination of behavioral, sociocultural, biological, and programmatic factors.