Occurrence of perfluoroalkyl substances in matched human serum, urine, hair and nail
Occurrence of perfluoroalkyl substances in matched human serum, urine, hair and nail
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匹配的人血清、尿液、头发和指甲中存在全氟烷基物质
DOI：
10.1016/j.jes.2017.08.017
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发表时间：
2018
影响因子：
6.9
通讯作者：
Wu Yongning
中科院分区：
文献类型：
--
作者：
Wang Yuxin;Zhong Yuxin;Li Jingguang;Zhang Jianqing;Lyu Bing;Zhao Yunfeng;Wu Yongning
本研究的目的是测定一般人群血清、尿液、头发和指甲中的全氟烷基物质（PFASs），探讨尿液、头发和指甲作为PFASs暴露生物监测样品的可能性。我们检测了深圳地区39份人体血清、尿液、头发和指甲中PFHxA、PFOA、PFNA、PFDA、PFUnDA、PFDoA、PFHxS和PFOS的浓度。四种基质中PFOS的检出频率和中位浓度均高于其他PFASs。血清、尿液、头发和指甲中的全氟辛烷磺酸浓度中位数分别为9.24纳克/毫升、13.96纳克/升、0.58纳克/克和0.63纳克/克。斯皮尔曼相关性检验结果表明，指甲是PFOS生物监测的理想基质，而非一般人群的尿液和头发。
The purpose of this study was to determine perfluoroalkyl substances (PFASs) in human serum, urine, hair and nail from general populations, and to investigate the possibility for human urine, hair and nail used as the biomonitoring sample for PFASs exposure. We detected the concentrations of PFHxA, PFOA, PFNA, PFDA, PFUnDA, PFDoA, PFHxS and PFOS in 39 matched human serum, urine, hair and nail samples from Shenzhen in China. The detection frequency and the median level of PFOS were all higher than that of the other PFASs in four matrices. The median concentration of PFOS in serum, urine, hair, and nail were 9.24 ng/mL, 13.96 ng/L, 0.58 ng/g and 0.63 ng/g, respectively. The results of spearman correlation test indicated that nail was an ideal matrix for biomonitoring PFOS rather than human urine and hair in general populations for the non-invasive sampling.