Forensic DNA testing.
Forensic DNA testing.
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DOI：
10.1101/pdb.top066928
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发表时间：
2011-12-01
影响因子：
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通讯作者：
Butler, John M
中科院分区：
文献类型：
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作者：
Butler, John M
法医DNA测试有许多应用，包括亲子鉴定，识别自然或人为灾害或恐怖袭击中的人类遗骸，以及解决犯罪问题。本文提供了背景信息，然后概述了法医DNA检测的过程，包括样本收集，DNA提取，PCR扩增，短串联重复序列（STR）等位基因分离和大小，分型和轮廓解释，统计分析和质量保证。文章最后讨论了数据和其他法医DNA检测技术可能存在的问题。
Forensic DNA testing has a number of applications, including parentage testing, identifying human remains from natural or man-made disasters or terrorist attacks, and solving crimes. This article provides background information followed by an overview of the process of forensic DNA testing, including sample collection, DNA extraction, PCR amplification, short tandem repeat (STR) allele separation and sizing, typing and profile interpretation, statistical analysis, and quality assurance. The article concludes with discussions of possible problems with the data and other forensic DNA testing techniques.