Brain activation by central command during actual and imagined handgrip under hypnosis.
Brain activation by central command during actual and imagined handgrip under hypnosis.
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在催眠状态下实际和想象的握力过程中，中央命令激活大脑。
DOI：
10.1152/japplphysiol.00939.2001
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Morgan,WP
中科院分区：
文献类型：
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作者：
Williamson,JW;McColl,R;Mathews,D;Mitchell,JH;Raven,PB;Morgan,WP
目的是比较想象握力练习中大脑的激活模式，并确定参与“中枢”心血管调节的大脑皮层结构。接受催眠性筛选的受试者，其中5人得分较高(HH)，4人得分较低(LH)，分别在两种情况下进行测试：1)在最大自主收缩(MVC)30%时进行静态握力练习(HG)，2)在30%MVC时想象HG(I-HG)。用单因素方差分析比较用力(Kg)、前臂综合肌电、感觉用力等级、心率(HR)、平均血压(MBP)以及局部脑血流分布的差异。HG期间，两组心率(+13±5次/min)和MBP(+17±3 mm Hg)在HG后3min有相似的增加。然而，在I-HG期间，只有HH组的HR(+10±2次/min；P<0.05)和MBP(+12±2 mm Hg；P<；0.05)增加。在I-HG期间，两组之间的力量或积分肌电活动没有显著增加或差异。在I-HG期间，HH组的体力消耗评分显著增加，而LH组则无显著差异。在局部脑血流量方面，I-HG期间，黄体生成素在前扣带回(−6±2%)和岛叶皮质(−9±4%)的活性显著降低。这些发现表明，想象运动引起的心血管反应涉及岛叶和前扣带回皮质的中枢激活，独立于肌肉传入反馈；这些结构似乎在心血管反应的中枢调节中起关键作用。
The purpose was to compare patterns of brain activation during imagined handgrip exercise and identify cerebral cortical structures participating in “central” cardiovascular regulation. Subjects screened for hypnotizability, five with higher (HH) and four with lower hypnotizability (LH) scores, were tested under two conditions involving 3 min of1) static handgrip exercise (HG) at 30% of maximal voluntary contraction (MVC) and2) imagined HG (I-HG) at 30% MVC. Force (kg), forearm integrated electromyography, rating of perceived exertion, heart rate (HR), mean blood pressure (MBP), and differences in regional cerebral blood flow distributions were compared using an ANOVA. During HG, both groups showed similar increases in HR (+13 ± 5 beats/min) and MBP (+17 ± 3 mmHg) after 3 min. However, during I-HG, only the HH group showed increases in HR (+10 ± 2 beats/min;P< 0.05) and MBP (+12 ± 2 mmHg;P< 0.05). There were no significant increases or differences in force or integrated electromyographic activity between groups during I-HG. The rating of perceived exertion was significantly increased for the HH group during I-HG, but not for the LH group. In comparison of regional cerebral blood flow, the LH showed significantly lower activity in the anterior cingulate (−6 ± 2%) and insular cortexes (−9 ± 4%) during I-HG. These findings suggest that cardiovascular responses elicited during imagined exercise involve central activation of insular and anterior cingulate cortexes, independent of muscle afferent feedback; these structures appear to have key roles in the central modulation of cardiovascular responses.