Sugar Beverages and Dietary Sodas Impact on Brain Health: A Mini Literature Review.
Sugar Beverages and Dietary Sodas Impact on Brain Health: A Mini Literature Review.
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DOI：
10.7759/cureus.2756
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发表时间：
2018-06-07
期刊：
影响因子：
--
通讯作者：
Ans AH
中科院分区：
文献类型：
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作者：
Anjum I;Jaffery SS;Fayyaz M;Wajid A;Ans AH
如今，含有咖啡因的含糖饮料在人类中广泛使用，会对整体健康产生负面影响。我们的研究旨在讨论这些含糖饮料 (SSB) 的影响，以及它们如何以不同方式影响健康，尤其是对大脑的影响。软饮料产生不良影响的一些机制包括谷胱甘肽 6 脱氢酶水平增加、γ-氨基丁酸 (GABA) 水平增加、脑电图 (EEG) 脑电波中谷氨酸和多巴胺的改变，最终导致中风和痴呆。它们可以通过减少单胺氧化酶和乙酰胆碱酯酶以及谷胱甘肽和过氧化氢酶等抗氧化剂来增加氧化应激。睡眠质量和睡眠持续时间也因其消耗量的增加而受到显着影响。 此外，人们还强调，摄入苯甲酸钠（存在于饮料中）会损害记忆力、运动协调性、影响还原型谷胱甘肽 (GSH)、增加大脑中的丙二醛 (MDA) 水平并导致儿童注意力缺陷多动障碍 (ADHD)。最后，我们将强调无糖饮料也可能有害，并且母亲在怀孕和产后期间食用巧克力或软饮料可能与认知障碍和儿童肥胖有关。
Sugar-sweetened beverages containing caffeine are widely used among humans nowadays and can have negative consequences on the overall health. Our study aims to discuss the effects of these sugar-sweetened beverages (SSB) and how they can impact the health in different ways particularly on the brain. Some of the mechanisms by which soft drinks can exert adverse effects include an increase in glutathione-6-dehydrogenase level, increased levels of gamma-aminobutyric acid (GABA), glutamate and dopamine alteration in brain waves on electroencephalography (EEG) eventually leading to stroke and dementia. They can increase the oxidative stress by a decreasing monoamine oxidase and acetylcholine esterase and antioxidants such as glutathione and catalase. The sleep quality and duration of sleep is also significantly affected by their increased consumption. Also, the consumption of sodium benzoate (found in beverages) on impairing memory, motor coordination, affecting reduced glutathione (GSH), increasing the malondialdehyde (MDA) level in the brain and producing attention deficit hyperactivity disorder (ADHD) in children is emphasized. Finally, we will highlight how diet drinks can also be harmful and the maternal consumption of chocolate or soft drinks during pregnancy and postnatal period can be linked to cognitive impairment and child obesity.