Genetic landscape and ligand-dependent activation of sonic hedgehog-Gli1 signaling in chordomas: a novel therapeutic target
Genetic landscape and ligand-dependent activation of sonic hedgehog-Gli1 signaling in chordomas: a novel therapeutic target
复制标题
脊索瘤中声波刺猬-Gli1信号的遗传景观和配体依赖性激活:一个新的治疗靶点
DOI:
10.1038/s41388-020-1324-2
复制
发表时间:
2020-05
期刊:
影响因子:
8
通讯作者:
Xiaoguang Liu
中科院分区:
文献类型:
--
作者:
Chenlong Yang;Lei Yong;Chen Liang;Yan Li;Yunlong Ma;Feng Wei;Liang Jiang;Hua Zhou;Guanping He;Xiaoyu Pan;Bao Hai;Jian Wu;Yulun Xu;Zhongjun Liu;Xiaoguang Liu
Chordoma, a rare neoplasm derived from intraosseous notochordal remnants, is unresponsive to conventional chemotherapy and radiotherapy. Sonic Hedgehog (Shh) is a crucial fetal notochord–secreted morphogen that directs notochordal development. The aim of
登录
查看更多内容
影响因子:
--
作者:
Armas-López L;Zúñiga J;Arrieta O;Ávila-Moreno F
通讯作者:
Ávila-Moreno F
影响因子:
2.5
作者:
Choi, Kyung-Suk;Cohn, Martin J.;Harfe, Brian D.
通讯作者:
Harfe, Brian D.
DOI:
10.1073/pnas.1601252113
发表时间:
2016-03
期刊:
Proceedings of the National Academy of Sciences
影响因子:
--
作者:
Jianjian Zhu;K. Kwan;S. Mackem
通讯作者:
Jianjian Zhu;K. Kwan;S. Mackem
DOI:
10.1073/pnas.0813203106
发表时间:
2009-03-17
影响因子:
11.1
作者:
Tian, Hua;Callahan, Christopher A.;de Sauvage, Frederic J.
通讯作者:
de Sauvage, Frederic J.
影响因子:
1.5
作者:
Sebaugh, J. L.
通讯作者:
Sebaugh, J. L.