Some features of the submicroscopic morphology of synapses in frog and earthworm.
Some features of the submicroscopic morphology of synapses in frog and earthworm.
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DOI：
10.1083/jcb.1.1.47
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发表时间：
1955-01
期刊：
影响因子：
--
通讯作者：
BENNETT, H S
中科院分区：
文献类型：
--
作者：
DE ROBERTIS, E D;BENNETT, H S
电子显微照片显示了青蛙交感神经节和蚯蚓神经索神经桩切片中遇到的突触区域。突触前和突触后神经元元件似乎各自具有 70 至 100 A 厚的膜，在突触区域上通过 100 至 150 A 宽的膜间空间彼此分开。颗粒状或囊泡成分，这里称为突触小泡，出现在突触的突触前侧，由许多直径为 200 至 500 A 的椭圆形或球形体组成，具有致密的圆周和较浅的中心。突触小泡与突触膜关系密切。在蚯蚓神经绒中，发现细长的囊泡延伸穿过突触前膜的穿孔或间隙，部分囊泡出现在膜间隙中。线粒体出现在突触附近，而在青蛙中，在突触前成员中可以看到亚显微丝状成分，其延伸到发现囊泡的区域，但终止于突触本身附近。
Electron micrographs are presented of synaptic regions encountered in sections of frog sympathetic ganglia and earthworm nerve cord neuropile. Pre- and postsynaptic neuronal elements each appear to have a membrane 70 to 100 A thick, separated from each other over the synaptic area by an intermembranal space 100 to 150 A across. A granular or vesicular component, here designated the synaptic vesicles, is encountered on the presynaptic side of the synapse and consists of numerous oval or spherical bodies 200 to 500 A in diameter, with dense circumferences and lighter centers. Synaptic vesicles are encountered in close relationship to the synaptic membrane. In the earthworm neuropile elongated vesicles are found extending through perforations or gaps in the presynaptic membrane, with portions of vesicles appearing in the intermembranal space. Mitochondria are encountered in the vicinity of the synapse, and in the frog, a submicroscopic filamentary component can be seen in the presynaptic member extending up to the region where the vesicles are found, but terminating short of the synapse itself.