A transcranial magnetic stimulation study of information processing in the motor cortex:: Relationship between the silent period and the reaction time delay
A transcranial magnetic stimulation study of information processing in the motor cortex:: Relationship between the silent period and the reaction time delay
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DOI：
10.1017/s0048577201392119
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发表时间：
2002-03-01
期刊：
影响因子：
3.7
通讯作者：
Hasbroucq, T
中科院分区：
文献类型：
--
作者：
Burle, B;Bonnet, M;Hasbroucq, T
本研究旨在解读持续肌电图中运动皮层经颅磁刺激（TMS）引起的选择反应时间（RT）和沉默期（SP）的延迟是否是由于相同的生理机制。为此，我们对 6 名健康志愿者执行双手选择 RT 任务时的 TMS 效果进行了研究。具体预测源自受“推迟阶段”假说启发的逻辑（Pashler & Johnson，1989）。当受刺激的皮层参与反应时，该逻辑预测 SP 持续时间和 RT 之间存在相关性，而当在 RT 间隔期间稍后传递刺激时，相关性更强。 TMS 对 RT 的影响是双重的：在早期刺激时间，刺激缩短了 RT，并且这种影响与随后反应中受刺激的运动皮层的参与无关。在稍后的刺激时间，TMS 会产生破坏性效果，前提是受刺激的皮层参与反应。当受刺激的皮层参与反应时，SP和RT之间存在相关性；当刺激发生较晚时，这种相关性更强。相反，当皮层不受刺激时，这两个变量之间不存在相关性。
The present study was aimed at deciphering whether the delay in choice reaction time (RT) and the silent period (SP) caused by transcranial magnetic stimulation (TMS) of the motor cortex in the ongoing electromyogram are due to the same physiological mechanism. To this end, the effect of TMS was studied in 6 healthy volunteers performing a between-hand choice RT task. Specific predictions were derived from a logic inspired from the "postponed stages" hypothesis (Pashler & Johnson, 1989). This logic predicts a correlation between SP duration and RT when the stimulated cortex is involved in the response, and a stronger correlation when the stimulation is delivered later during the RT interval. The effect of TMS on RT was twofold: At early stimulation times, the stimulation shortened the RT and this effect was independent of the involvement of the stimulated motor cortex in the subsequent response. At later stimulation times, TMS had a disruptive effect, provided that the stimulated cortex was involved in the response. When the stimulated cortex was involved in the response, there was a correlation between SP and RT; this correlation was stronger when the stimulation occurred later. In contrast, there was no correlation between these two variables when the stimulated cortex was not involved.