The Safety of Maternal and Fetal MRI at 3 T
The Safety of Maternal and Fetal MRI at 3 T
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DOI：
10.2214/ajr.19.21400
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发表时间：
2019-11-01
影响因子：
5
通讯作者：
Marks, Robert M.
中科院分区：
文献类型：
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作者：
Chartier, Andre L.;Bouvier, Monique J.;Marks, Robert M.
目标。本研究的目的是评价临床3-F-MRI对先天性听力障碍、脑或染色体异常低风险新生儿的胎儿生长发育和新生儿听力的影响。这项单中心回顾性病例对照研究包括2008年1月至2015年3月期间出生的连续出生的健康新生儿，在MRI期间因母体或胎儿的指征而在宫内暴露于3-T磁共振。每个接触MR的新生儿按出生日期1：2随机配对，与未接触MR的健康对照组新生儿出生体重比较采用非配对t检验。结果MR组新生儿平均出生体重(3398 G)与对照组(3510 G)比较差异无统计学意义(p=0.06)。在MR暴露组(0%[0/81])和对照组(1.8%[3/162])之间，听力损害的发生率没有显著差异(p=0.55)。结论：本研究显示，在任何孕龄的不同临床母儿或胎儿指征期间，在宫内接受不同的3-T MR照射对新生儿听力或胎儿生长没有不良影响。
OBJECTIVE. The purpose of this study was to evaluate the effects of clinical 3-F MRI during pregnancy on fetal growth and neonatal hearing in neonates at low risk of congenital hearing impairment or of brain or chromosomal abnormalities.MATERIALS AND METHODS. This single-center retrospective case-control study included consecutively born healthy neonates exposed in utero to 3-T MR during MRI for maternal or fetal indications and born between January 2008 and March 2015. Each exposed neonate was randomly matched 1:2 by birth date to healthy control neonates who had not been exposed to MR Infant birth weights were compared by unpaired t test. Hearing impairment between groups was compared by Fisher exact test.RESULTS. There was no significant difference in mean birth weight between the MR-exposed (3398 g) and control (3510 g) neonates (p = 0.06). There was no significant difference in prevalence of hearing impairment (p = 0.55) between the MR-exposed (0% [0/81]) and control (1.8%[3/162]) groups.CONCLUSION. This study showed no adverse effects with regard to neonatal hearing or fetal growth in healthy neonates who were variably exposed to 3-T MR in utero during MRI for various clinical maternal or fetal indications at any gestational age.