Equilibrium Analysis of Acid Dissociation Reactions of Phenolphthalein by Using Mobility Change in Capillary Zone Electrophoresis
Equilibrium Analysis of Acid Dissociation Reactions of Phenolphthalein by Using Mobility Change in Capillary Zone Electrophoresis
复制标题
利用毛细管区带电泳迁移率变化分析酚酞酸解离反应的平衡
DOI：
10.1246/cl.2001.14
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发表时间：
2001
影响因子：
1.6
通讯作者：
S. Motomizu
中科院分区：
文献类型：
--
作者：
T. Takayanagi;S. Motomizu
用毛细管区带电泳平衡分析法测定了在碱性水溶液中不稳定的酚酞的酸离解常数。酚酞的表观电泳迁移率随迁移溶液pH值的增加而增加。酚酞的酸解离常数（pKa）测定为8.84和9.40，通过应用非线性最小二乘分析的迁移率变化。
An equilibrium analysis method by capillary zone electrophoresis was utilized for the determination of acid dissociation constants of phenolphthalein, which is unstable in an alkaline aqueous solution. Apparent electrophoretic mobility of phenolphthalein increased with increasing pH of a migrating solution. Acid dissociation constants (pKa) of phenolphthalein were determined as 8.84 and 9.40 by applying a non-linear least-squares analysis to the mobility change.