Hemispheric asymmetries and schizophrenia.
Hemispheric asymmetries and schizophrenia.
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DOI：
10.1176/ajp.139.4.427
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发表时间：
1982-04
期刊：
影响因子：
--
通讯作者：
N. Andreasen;J. Dennert;S. Olsen;A. Damasio
中科院分区：
文献类型：
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作者：
N. Andreasen;J. Dennert;S. Olsen;A. Damasio
研究者假设精神分裂症患者左半球功能异常或偏离正常功能不对称。也有人认为精神分裂症患者具有正常结构不对称的逆转。作者测量了43例右利手精神分裂症患者和40例右利手对照者的额叶和枕叶花瓣以及大脑各半球的额叶和枕叶宽度。两组之间的结构不对称性没有显著差异。8例左撇子精神分裂症患者可能有异常的功能不对称，他们的平均脑室-脑比，一个可能的间接指标的脑萎缩，高于右利手的患者。
Investigators have hypothesized that schizophrenic patients have abnormal left hemisphere function or deviations from normal function asymmetry. It has also been suggested that schizophrenic patients have reversal of normal structural asymmetries. The authors measured frontal and occipital petalia and frontal and occipital width of each hemisphere on the CT scans of 43 right-handed schizophrenic patients and 40 right-handed control subjects. There were no significant differences in structural asymmetry between the groups. The 8 left-handed schizophrenic patients may have had abnormal functional asymmetries; their mean ventricular-brain ratio, a possible indirect indicator of cerebral atrophy, was higher than that of the right-handed patients.