ROLE OF DIET IN THE DETERMINATION OF JEJUNAL SUCRASE ACTIVITY IN THE WEANLING RAT
ROLE OF DIET IN THE DETERMINATION OF JEJUNAL SUCRASE ACTIVITY IN THE WEANLING RAT
复制标题
DOI：
10.1203/00006450-198107000-00019
复制
发表时间：
1981-01-01
影响因子：
3.6
通讯作者：
GUERIN, DM
中科院分区：
文献类型：
--
作者：
HENNING, SJ;GUERIN, DM
研究了大鼠乳和大鼠饲料对生后第4周空肠蔗糖酶活性影响的关键差异。在出生后第17天将大鼠断奶至特殊饮食，并在第28天测定空肠蔗糖酶。以乳糖为唯一碳水化合物的颗粒饲料不会引起蔗糖酶活性的降低。蔗糖酶值（μ mol/h/mg蛋白质）为10.49 ±。0.81（n = 15）和6.65 . ±. 0.29（n = 16）。膳食碳水化合物的性质显然不能解释断奶和未断奶动物蔗糖酶的差异。饮食的物理一致性并不重要，因为蔗糖酶值在流质饮食中同样高（10.91 ± 0.01）。0.77μ mol/h/mg蛋白质; n = 8）。当饮食中碳水化合物和脂肪的相对比例变化时，对蔗糖酶活性有显著影响;低碳水化合物饮食的值（4.30 ± 0.01）。0.33μ mol/h/mg蛋白质; n = 8）低于高碳水化合物饮食的1/2（10.91 ± 0.05 μ mol/h/mg蛋白质; n = 8）。0.77μ mol/h/mg蛋白质; n = 8）。
The critical difference between rat milk and rat chow with respect to their effects on jejunal sucrase activity during the 4th postnatal week was studied. Rats were weaned onto special diets on postnatal day 17 and jejunal sucrase was assayed on day 28. A pelleted diet containing lactose as sole carbohydrate did not cause depression of sucrase activity. Sucrase values (.mu.mol/h per mg protein) were 10.49 .+-. 0.81 (n = 15) for the lactose chow and 6.65 .+-. 0.29 (n = 16) for the sucrose chow. The nature of the dietary carbohydrate apparently does not account for the sucrase differences of weaned and nonweaned animals. The physical consistency of the diet is unimportant because sucrase values were just as high on a liquid diet (10.91 .+-. 0.77 .mu.mol/h per mg protein; n = 8) as on the solid diets. When the relative proportions of carbohydrate and fat in the diet were varied, there were significant effects on sucrase activity; values on a low carbohydrate diet (4.30 .+-. 0.33 .mu.mol/h per mg protein; n = 8) being less than 1/2 those on a high carbohydrate diet (10.91 .+-. 0.77 .mu.mol/h per mg protein; n = 8).