EXTRA-ABDOMINAL DESMOID TUMORS

EXTRA-ABDOMINAL DESMOID TUMORS
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DOI:
10.2106/00004623-198466090-00007
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发表时间:
1984-01-01
影响因子:
5.3
通讯作者:
BREWSTER, RC
BREWSTER, RC
中科院分区:
医学1区
文献类型:
--
作者:
ROCK, MG;PRITCHARD, DJ;BREWSTER, RC

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患有腹外硬纤维瘤的患者在梅奥诊所接受治疗,其中大多数位于四肢。在194人中,68%132人在第一次治疗后平均1.4年内复发。女性、30岁以上的患者、某些解剖部位(特别是足部和小腿)的复发倾向更明显,最重要的是,在接受了病灶内或边缘切除的治疗后。考虑到生存预后良好,在解剖可行或边缘切除的情况下,推荐广泛的局部切除,如果进行宽缘切除会严重损害肢体功能,则建议术后进行放射治疗。不再生长的复发性病变应该被追踪,直到病变生长的证据促使二次广泛切除。
Patients with extra-abdominal desmoid tumors, most of them in the extremities, were treated at the Mayo Clinic. Of the 194, 68% 132 experienced a recurrence at an average of 1.4 yr after the 1st treatment. A greater tendency for recurrence was evident in females, in patients older than 30 yr, in certain anatomical locations (especially the foot and calf), and most importantly, after treatment by intralesional or marginal excision. In view of the excellent prognosis for survival, wide local excision is recommended when anatomically feasible or marginal excision and postoperative radiation therapy when function of the extremity would be severely compromised if excision with wide margins were done. A recurrent lesion that does not appear to be growing should be followed until evidence of growth of the lesion precipitates a secondary wide excision.