Diameter of the cell-to-cell junctional membrane channels as probed with neutral molecules.

Diameter of the cell-to-cell junctional membrane channels as probed with neutral molecules.
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用中性分子探测的细胞间连接膜通道的直径。

DOI:
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发表时间:
1981
期刊:
影响因子:
56.9
通讯作者:
W. Loewenstein
W. Loewenstein
中科院分区:
综合性期刊1区
文献类型:
--
作者:
G. Schwarzmann;H. Wiegandt;B. Rose;A. Zimmerman;D. Ben;W. Loewenstein

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用荧光分子中性线性寡糖、中性分支糖肽和带电线性肽探测昆虫唾液腺和培养的昆虫和哺乳动物细胞的连接处的细胞-细胞通道。从最大的渗透物和最小的不渗透物的分子尺寸,获得了渗透限制通道直径:哺乳动物细胞为16至20埃,昆虫细胞为20至30埃。
The cell-to-cell channels in the junctions of an insect salivary gland and of insect and mammalian cells in culture were probed with fluorescent molecules-neutral linear oligosaccharides, neutral branched glycopeptides, and charged linear peptides. From the molecular dimensions of the largest permeants and smallest impermeants the permeation-limiting channel diameter was obtained: 16 to 20 angstroms for the mammalian cells and 20 to 30 angstroms for the insect cells.