Theoretical evaluation of the susceptometric measurement of iron in human liver by four different susceptometers
Theoretical evaluation of the susceptometric measurement of iron in human liver by four different susceptometers
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DOI：
10.1088/0967-3334/23/4/308
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发表时间：
2002-11-01
影响因子：
3.2
通讯作者：
Zago, MA
中科院分区：
文献类型：
--
作者：
Carneiro, AAO;Baffa, O;Zago, MA
本文利用模拟肝区磁化率测量对肝铁定量进行了评价。考虑了具有均匀和非均匀磁场的悬浮式磁强计与轴向二阶和平面一阶梯度磁探测器的耦合。考虑到样品的体积和磁化率分别相当于肝铁、组织和肺空气，评估了穿过探测器线圈的磁通强度。这些体积由圆柱体和球体几何表示。对四种配置的磁感仪测量肝组织中铁超载的主要误差来源进行了评估。
This paper is an evaluation of liver iron quantification using a simulated magnetic susceptibility measurement in the hepatic region. Susceptometers having homogeneous and non-homogeneous magnetizing fields coupled with axial second-order and planar first-order gradiometric magnetic detectors were considered. The intensity of magnetic flux threading the detector coils was evaluated considering samples with volume and susceptibility equivalent to liver iron, tissue and lung air individually. These volumes were represented by cylindrical and spherical geometries. The main sources of error in quantifying iron overload in susceptometric measurement of hepatic tissue were evaluated for four configurations of the susceptometer.