Recent trends in breast cancer incidence in US white women by county-level urban/rural and poverty status.
Recent trends in breast cancer incidence in US white women by county-level urban/rural and poverty status.
复制标题
县级城市/农村和贫困状况，美国白人妇女乳腺癌发病率的最新趋势。
DOI：
10.1186/1741-7015-7-31
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发表时间：
2009-06-26
期刊：
影响因子：
9.3
通讯作者：
Clarke CA
中科院分区：
文献类型：
--
作者：
Hausauer AK;Keegan TH;Chang ET;Glaser SL;Howe H;Clarke CA
2001年至2004年，美国浸润性乳腺癌发病率出现前所未有的下降，特别是50岁以上的非西班牙裔白色妇女中雌激素受体阳性肿瘤。为了了解这些减少在以前未研究的人群中更广泛的公共卫生意义，我们利用美国最大的癌症登记资源来描述年龄调整后的浸润性和原位乳腺癌发病率趋势，非西班牙裔白色妇女年龄在50至74岁之间，并按县级农村/城市和贫困状况分类。我们从参与北美中央癌症登记协会资源的29个基于人群的癌症登记处获得了1997年至2004年的浸润性和原位乳腺癌发病率数据。年年龄调整率进行了检查，整体和农村/城市和贫困的病人的居住县在诊断。联合点回归用于评估诊断的年度季度趋势。2001年至2004年期间，浸润性乳腺癌总发病率下降了13.2%，城市（-13.8%）和农村（-7.5%）以及低贫困县（-13.0%）或中贫困县（-13.8%）和高贫困县（-9.6%）妇女的发病率下降幅度更大。大多数发病率在1999年左右达到高峰，然后在2002年第二季度后下降，尽管在农村县，发病率在1999年后单调下降。在原位癌中观察到类似但更减弱的模式。城市和低贫困、富裕县的乳腺癌发病率下降幅度大于农村或高贫困县。这些模式可能反映了2002年7月后激素治疗使用减少的主要影响，但不能排除由于筛查模式可能产生的影响，特别是在激素治疗使用可能不太普遍的农村人口中。
Unprecedented declines in invasive breast cancer rates occurred in the United States between 2001 and 2004, particularly for estrogen receptor-positive tumors among non-Hispanic white women over 50 years. To understand the broader public health import of these reductions among previously unstudied populations, we utilized the largest available US cancer registry resource to describe age-adjusted invasive and in situ breast cancer incidence trends for non-Hispanic white women aged 50 to 74 years overall and by county-level rural/urban and poverty status. We obtained invasive and in situ breast cancer incidence data for the years 1997 to 2004 from 29 population-based cancer registries participating in the North American Association of Central Cancer Registries resource. Annual age-adjusted rates were examined overall and by rural/urban and poverty of patients' counties of residence at diagnosis. Joinpoint regression was used to assess trends by annual quarter of diagnosis. Between 2001 and 2004, overall invasive breast cancer incidence fell 13.2%, with greater reductions among women living in urban (-13.8%) versus rural (-7.5%) and low- (-13.0%) or middle- (-13.8%) versus high- (-9.6%) poverty counties. Most incidence rates peaked around 1999 then declined after second quarter 2002, although in rural counties, rates decreased monotonically after 1999. Similar but more attenuated patterns were seen for in situ cancers. Breast cancer rates fell more substantially in urban and low-poverty, affluent counties than in rural or high-poverty counties. These patterns likely reflect a major influence of reductions in hormone therapy use after July 2002 but cannot exclude possible effects due to screening patterns, particularly among rural populations where hormone therapy use was probably less prevalent.
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影响因子：
10.3
作者：
Glass, Andrew G.;Lacey, James V., Jr.;Hoover, Robert N.
通讯作者：
Hoover, Robert N.
影响因子：
7.2
作者：
Buist, DSM;Newton, KM;Kessler, L
通讯作者：
Kessler, L
影响因子：
5
作者：
DEVESA, SS;DONALDSON, J;FEARS, T
通讯作者：
FEARS, T
影响因子：
120.7
作者：
Gapstur, SM;Morrow, M;Sellers, TA
通讯作者：
Sellers, TA
影响因子：
39.2
作者：
Haas, JS;Kaplan, CP;Kerlikowske, K
通讯作者：
Kerlikowske, K