Highly Sensitive Surface Enhanced Raman Scattering Substrates Based on Filter Paper Loaded with Plasmonic Nanostructures
Highly Sensitive Surface Enhanced Raman Scattering Substrates Based on Filter Paper Loaded with Plasmonic Nanostructures
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DOI：
10.1021/ac2016882
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发表时间：
2011-12-01
影响因子：
7.4
通讯作者：
Singamaneni, Srikanth
中科院分区：
文献类型：
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作者：
Lee, Chang H.;Hankus, Mikella E.;Singamaneni, Srikanth
我们报告了一种新的表面增强拉曼散射（Sers）基板平台的基础上，一个共同的滤纸吸附等离子体纳米结构，克服了许多与现有的Sers基板的挑战。纸基设计的结果在基板，结合了所有的优势，传统的刚性和平面Sers基板在一个动态的灵活的脚手架格式。在本文中，我们讨论了我们的新型基板使用非共振分析物的制造，物理特性和Sers活性。SEAS基板被发现是高度敏感的，强大的，和和蔼可亲的几个不同的环境和目标分析物。它还具有成本效益，并展示了高样品收集效率，并且不需要复杂的制造方法。该方法灵敏度高（0.5nM反式-1，2-双（4-吡啶基）乙烯（BPE）），重现性好（相对标准偏差（RSD）约为15%）。这里展示的纸衬底建立了一个新的平台，用于将Sers与现有的分析技术（如色谱和微流体）相结合，赋予这些技术化学特异性。
We report a novel surface enhanced Raman scattering (SERS) substrate platform based on a common filter paper adsorbed with plasmonic nanostructures that overcomes many of the challenges associated with existing SERS substrates. The paper-based design results in a substrate that combines all of the advantages of conventional rigid and planar SERS substrates in a dynamic flexible scaffolding format. In this paper, we discuss the fabrication, physical characterization, and SERS activity of our novel substrates using nonresonant analytes. The SEAS substrate was found to be highly sensitive, robust, and amiable to several different environments and target analytes. It is also cost-efficient and demonstrates high sample collection efficiency and does not require complex fabrication methodologies. The paper substrate has high sensitivity (0.5nM trans-1,2-bis(4-pyridyl)ethene (BPE)) and excellent reproducibility (similar to 15% relative standard deviation (RSD)). The paper substrates demonstrated here establish a novel platform for integrating SERS with already existing analytical techniques such as chromatography and microfluidics, imparting chemical specificity to these techniques.