Global Consensus on Keratoconus and Ectatic Diseases

Global Consensus on Keratoconus and Ectatic Diseases
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DOI:
10.1097/ico.0000000000000408
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发表时间:
2015-04-01
期刊:
影响因子:
2.8
通讯作者:
Sangwan, Virender S.
Sangwan, Virender S.
中科院分区:
医学3区
文献类型:
--
作者:
Gomes, Jose A. P.;Tan, Donald;Sangwan, Virender S.

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背景:尽管对圆锥角膜和扩张性角膜疾病的诊断和治疗有广泛的认识,但仍然存在许多争议。目的:本项目旨在使世界各地的眼科专家就圆锥角膜和扩张性疾病的定义、概念、临床处理和手术治疗达成共识。方法:采用Delphi方法进行3轮问卷调查,并辅以面对面的会议。36名小组成员被分配到3个小组中的1个:定义/诊断、非手术治疗或手术治疗。结果:在圆锥角膜和其他扩张性疾病的定义、诊断方法和处理方面产生了大量的一致意见。对于这些疾病的非手术和手术治疗,包括使用角膜交联术和角膜移植,都是循序渐进的。建立了圆锥角膜合理处理顺序的流程图。结论:本项目为圆锥角膜和其他扩张性疾病的诊断和治疗提供了定义、陈述和建议。它还提供了对当前世界范围内对这些疾病的治疗的洞察。
Background: Despite extensive knowledge regarding the diagnosis and management of keratoconus and ectatic corneal diseases, many controversies still exist. For that reason, there is a need for current guidelines for the diagnosis and management of these conditions.Purpose: This project aimed to reach consensus of ophthalmology experts from around the world regarding keratoconus and ectatic diseases, focusing on their definition, concepts, clinical management, and surgical treatments.Methods: The Delphi method was followed with 3 questionnaire rounds and was complemented with a face-to-face meeting. Thirty-six panelists were involved and allocated to 1 of 3 panels: definition/diagnosis, nonsurgical management, or surgical treatment. The level of agreement considered for consensus was two thirds.Results: Numerous agreements were generated in definitions, methods of diagnosing, and management of keratoconus and other ectatic diseases. Nonsurgical and surgical treatments for these conditions, including the use of corneal cross-linking and corneal transplantations, were presented in a stepwise approach. A flowchart describing a logical management sequence for keratoconus was created.Conclusions: This project resulted in definitions, statements, and recommendations for the diagnosis and management of keratoconus and other ectatic diseases. It also provides an insight into the current worldwide treatment of these conditions.