The Tromsø Study: identification of and a controlled intervention on a population of early-stage risk drinkers.
The Tromsø Study: identification of and a controlled intervention on a population of early-stage risk drinkers.
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特罗姆瑟研究：识别早期风险饮酒者群体并对其进行控制干预。
DOI：
10.1016/0091-7435(91)90049-a
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发表时间：
1991
影响因子：
5.1
通讯作者：
O. Nilssen
中科院分区：
文献类型：
--
作者：
O. Nilssen
背景：在一项对21,000多名年龄在12-62岁的男性和女性进行的健康调查中，γ-谷氨酰转移酶的测量和对五个关于酒精消费的问题的回答被用作选择早期危险饮酒者的干预人群的基础。共有290名男性和48名女性符合纳入标准。方法：338名受试者被随机分为对照组和两个干预组。较小的干预包括一次咨询，在此期间讨论了GGT升高的可能原因，并分发了一本小册子，其中载有关于改变饮酒习惯的建议。在主要干预组中，干预更具体地针对酒精，并对饮酒习惯进行了广泛的采访。结果：三组受试者在1年后均接受了GGT测定，并就过去一年饮酒习惯的改变进行了访谈。在随访时，与对照组相比，干预组的平均GGT(26.5U/L)和自我报告的酒精摄入量(24.7g/d)显著降低。然而，在干预组之间没有观察到显著的差异。结论本研究表明，适度和简单的干预可能会对早期危险饮酒者的饮酒习惯产生重要的改变。
Background.In a health survey of more than 21,000 men and women ages 12–62 years, measurement of γ-glutamyltransferase (GGT) and answers on five questions on alccohol consumption were used as a basis for selecting an intervention population of early-stage risk drinkers. Altogether 290 men and 48 women met the criteria for inclusion.Methods.The 338 subjects were randomized to a control group and two intervention groups. The minor interventions consisted of a single consultation during which possible reasons for the elevated GGT were discussed and a pamphlet with advice on changes in drinking habits was handed out. In the major intervention group the intervention was directed more specifically toward alcohol, with an extensive interview on drinking habits. In addition, the subjects in this group were offered follow-up consultations for new measurements of GGT.Results.All three groups were examined after 1 year with GGT determination and an interview on change in drinking habits during the past year. At follow-up, significant decreases in mean GGT (26.5 U/liter) and self-reported alcohol intake (24.7 g/day) were observed in the intervention groups compared with the control group. No significant differences were, however, observed between the intervention groups.Conclusion.The study indicates that modest and simple interventions may yield important changes in drinking habits in early-stage risk drinkers.