Serologic evidence of Lyssavirus infections among bats, the Philippines

Serologic evidence of Lyssavirus infections among bats, the Philippines
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DOI:
10.3201/eid0803.010330
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发表时间:
2002-03-01
影响因子:
11.8
通讯作者:
Rupprecht, CE
Rupprecht, CE
中科院分区:
医学2区
文献类型:
--
作者:
Arguin, PM;Murray-Lillibridge, K;Rupprecht, CE

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在菲律宾的蝙蝠种群中对狂犬病毒进行了积极的监测。过去或目前的狂犬病毒感染的存在下,确定通过使用直接荧光抗体测定蝙蝠大脑和蝙蝠血清中的病毒中和试验。虽然没有发现蝙蝠有活跃的感染与狂犬病病毒,22有证据的中和抗体对澳大利亚蝙蝠狂犬病病毒(ABLV)。血清阳性与一种蝙蝠,长翼蝠schreibersi统计。病毒中和试验的结果与菲律宾存在与ABLV相关的天然Lyssavirus一致。
Active surveillance for lyssaviruses was conducted among populations of bats in the Philippines. The presence of past or current Lyssavirus infection was determined by use of direct fluorescent antibody assays on bat brains and virus neutralization assays on bat sera. Although no bats were found to have active infection with a Lyssavirus, 22 had evidence of neutralizing antibody against the Australian bat lyssavirus (ABLV). Seropositivity was statistically associated with one species of bat, Miniopterus schreibersi. Results from the virus neutralization assays are consistent with the presence in the Philippines of a naturally occurring Lyssavirus related to ABLV.