The effect of noise and carbogen on cochlear vasculature.
The effect of noise and carbogen on cochlear vasculature.
复制标题
噪音和卡波金对耳蜗脉管系统的影响。
DOI：
10.3109/00016488409107537
复制
发表时间：
1984
影响因子：
1.4
通讯作者：
J. Wright
中科院分区：
文献类型：
--
作者：
H. Dengerink;A. Axelsson;J. Miller;J. Wright
对 24 只豚鼠进行了耳蜗脉管系统和血流的组织学测量。六只动物暴露于 120 dB SPL 的白噪声中，同时呼吸卡波根（10% CO2 和 90% O2）30 分钟。六名受试者在呼吸空气时暴露在噪音中。六名呼吸卡波金没有暴露于噪音，六名作为未暴露的空气呼吸对照。统计上显着的结果表明，噪音导致耳蜗的血液供应减少，而卡波金则增加了耳蜗的血流量。当动物同时暴露于噪音和卡波金时，卡波金往往会抵消噪音造成的血液供应减少的影响。
Histological measures of cochlear vasculature and blood flow were examined in 24 guinea pigs. Six animals were exposed to white noise at 120 dB SPL while breathing carbogen (10% CO2 and 90% O2) for 30 min. Six subjects were noise exposed while breathing air. Six breathed carbogen without noise exposure and six served as unexposed air-breathing controls. The statistically significant results indicate that noise resulted in reduced blood supply to the cochlea and that carbogen increased cochlear blood flow. When animals were exposed to both noise and carbogen, carbogen tended to counteract the reduced blood supply effects of noise.