Occurrence and risk assessment of antidepressants in Huangpu River of Shanghai, China
Occurrence and risk assessment of antidepressants in Huangpu River of Shanghai, China
复制标题
中国上海黄浦江流域抗抑郁药物的发生及风险评估
DOI：
10.1007/s11356-017-9293-x
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发表时间：
2017
影响因子：
5.8
通讯作者：
Xu G
中科院分区：
文献类型：
--
作者：
Wu Minghong;Xiang Jiajia;Chen Fenfen;Fu Cao;Xu Gang;Wu Minghong;Xu G
抗抑郁药越来越受到公众的关注，因为越来越多的报道称它们在环境中出现，并对生态系统和人类健康产生潜在影响。药物通过精神病院或污水处理厂的污水持续流入河流，可能对接收水体的水生生态系统造成不利影响。本研究调查了上海市黄浦江干支流中8种抗抑郁药物的发生及来源。所选抗抑郁药的检测浓度在主流中为低纳克/升至42.9纳克/升（氟西汀），在支流中为低纳克/升至33.7纳克/升（氟西汀）。为了研究医院或污水处理厂对环境的影响，对上下游样本进行了分析。一般来说，抗抑郁药在下游的浓度高于污水处理厂或医院的上游浓度。这表明污水处理厂和医院可能会给水环境带来污染。初步进行了风险评估：8种目标化合物的风险商（RQ）均未超过0.1，表明对水环境没有不良影响。本研究结果将为今后上海市抗抑郁药污染的控制和管理提供背景数据。
Antidepressants are gaining public attention because of increasing reports of their occurrence in environment and their potential impact on ecosystems and human health. Continuous input of pharmaceuticals into rivers, through psychiatric hospital or wastewater treatment plant (WWTPs) effluent, may cause adverse effects on the aquatic ecosystems of the receiving water bodies. This work investigates the occurrence and sources of 8 antidepressants in main stream and tributaries of Huangpu River in Shanghai. The detected concentrations of the selected antidepressants ranged from low nanogram per liter to 42.9 ng L−1(fluoxetine) in main stream and ranged from low nanogram per liter to 33.7 ng L−1(fluoxetine) in tributaries. To study the effect of hospital or wastewater treatment plants (WWTPs) on environment, the upstream and downstream samples were analyzed. Generally, antidepressants had greater concentrations in downstream than that in upstream of the WWTPs or hospitals. It is suggesting that WWTPs and hospitals may introduce pollution into water environment. A preliminary risk assessment was conducted: none of the eight target compounds yielded risk quotient (RQ) values more than 0.1, thus indicating that no adverse effect is expected in water environment. These results will provide background data for future antidepressants pollution control and management in Shanghai, China.