Imaging techniques for local recurrence of prostate cancer: for whom, why and how?
Imaging techniques for local recurrence of prostate cancer: for whom, why and how?
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DOI：
10.1016/j.diii.2012.01.012
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发表时间：
2012-04-01
影响因子：
5.5
通讯作者：
Rouviere, O
中科院分区：
文献类型：
--
作者：
Rouviere, O
由于存在挽救方案，因此尽早发现前列腺癌的局部复发非常重要。第一个迹象是“生化失败”，即前列腺特异性抗原（PSA）浓度再次升高。生化失败的定义因初始治疗而异：前列腺切除术后PSA大于0.2ng/mL，放疗后最低点+2ng/mL。冷冻疗法、聚焦超声或近距离放射治疗后生化失败没有标准化定义。磁共振成像（MRI）（特别是动态MRI）可以以良好的灵敏度检测局部复发。光谱学的作用仍在讨论中。目前，超声波技术的效果不如 MRI。
Since there are salvage solutions, it is important to detect local recurrence of prostate cancer as early as possible. The first sign is "biochemical failure" in that the prostate specific antigen (PSA) concentration rises again. The definition of biochemical failure varies depending on the initial treatment: PSA greater than 0.2ng/mL after prostatectomy, nadir+2ng/mL after radiotherapy. There is no standardised definition of biochemical failure after cryotherapy, focused ultrasound, or brachytherapy. Magnetic resonance imaging (MRI) (particularly dynamic MRI) can detect local recurrence with good sensitivity. The role of spectroscopy is still under discussion. For the moment, ultrasound techniques are less effective than MRI.