Head and Neck Cancers, Version 1.2015.

Head and Neck Cancers, Version 1.2015.
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DOI:
10.6004/jnccn.2015.0102
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发表时间:
2015-07
期刊:
Journal of the National Comprehensive Cancer Network : JNCCN
影响因子:
--
通讯作者:
Hughes M
Hughes M
中科院分区:
其他
文献类型:
--
作者:
Pfister DG;Spencer S;Brizel DM;Burtness B;Busse PM;Caudell JJ;Cmelak AJ;Colevas AD;Dunphy F;Eisele DW;Foote RL;Gilbert J;Gillison ML;Haddad RI;Haughey BH;Hicks WL Jr;Hitchcock YJ;Jimeno A;Kies MS;Lydiatt WM;Maghami E;McCaffrey T;Mell LK;Mittal BB;Pinto HA;Ridge JA;Rodriguez CP;Samant S;Shah JP;Weber RS;Wolf GT;Worden F;Yom SS;McMillian N;Hughes M

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这些NCCN指南见解重点关注2015年NCCN头颈部(H&N)癌症指南的最新更新。这些见解描述了可用于治疗H&N癌症的不同类型的粒子治疗,与传统的光子(X射线)放射治疗(RT)相反。目前正在研究不同类型的粒子治疗,包括质子和碳离子,目的是减少RT的长期副作用并提高治疗指数。对于2015年的更新,NCCN H&N癌症小组同意删除对唾液腺癌的中子治疗的建议,因为它的可用性有限,在过去的20年中已经减少;目前接受这种治疗的美国患者数量很少;以及担心中子治疗的毒性可能抵消潜在的疾病控制优势。
These NCCN Guidelines Insights focus on recent updates to the 2015 NCCN Guidelines for Head and Neck (H&N) Cancers. These Insights describe the different types of particle therapy that may be used to treat H&N cancers, in contrast to traditional radiation therapy (RT) with photons (x-ray). Research is ongoing regarding the different types of particle therapy, including protons and carbon ions, with the goals of reducing the long-term side effects from RT and improving the therapeutic index. For the 2015 update, the NCCN H&N Cancers Panel agreed to delete recommendations for neutron therapy for salivary gland cancers, because of its limited availability, which has decreased over the past 2 decades; the small number of patients in the United States who currently receive this treatment; and concerns that the toxicity of neutron therapy may offset potential disease control advantages.