Tracheobronchomalacia and Excessive Dynamic Airway Collapse
Tracheobronchomalacia and Excessive Dynamic Airway Collapse
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DOI：
10.1016/j.ccm.2013.05.003
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发表时间：
2013-09-01
影响因子：
5.7
通讯作者：
Colt, Henri
中科院分区：
文献类型：
--
作者：
Murgu, Septimiu;Colt, Henri
气管支气管软化和过度动态气道塌陷是呼气性中央气道塌陷的形态类型，具有特定的病理生理、病因和气道壁结构改变。照顾有症状的呼气性中央气道塌陷患者的医生必须定位适合支气管镜或手术干预的限流气道段。功能性支气管镜检查和动态放射学研究用于初步评估和设计随访策略。需要研究确定无创和可靠的生理方法来定位限流段，以指导患者选择治疗方案并预测干预措施的反应。
Tracheobronchomalacia and excessive dynamic airway collapse are morphologic types of expiratory central airway collapse with specific pathophysiology, cause, and structural changes in airway wall. Physicians caring for symptomatic patients with expiratory central airway collapse must localize the flow-limiting airway segments amenable to bronchoscopic or surgical interventions. Functional bronchoscopy and dynamic radiologic studies are performed for the initial evaluation and to design follow-up strategies. Research is needed to determine noninvasive and reliable physiologic methods for localizing the flow-limiting segments that might guide patient selection for treatment and predict response to interventions.